PEELING SKIN SYNDROME (PSS) is a very rare keratinization disorder, characterized by spontaneous exfoliation of the stratum corneum. Herein, we report a case of non-inflammatory (type A) PSS.

Background and aim: Diabetes mellitus is a metabolic disease with multiple complications. SKIN tag is a pedunculated papule, which is more common in women and has been suggested as a cutaneous marker of diabetes mellitus. The aim of this study was to determine the frequency of diabetes mellitus in patients with SKIN tags.Materials and methods: This descriptive study was done on 100 patients with SKIN tags. The investigation included fasting blood sugar (FBS) and glucose tolerance test (OTT).Results: 66 patients had normal FBS, 27 had diabetes mellitus, 5 had impaired OTT and 2 had impaired fasting glucose. Over all, 34 had abnormal glucose metabolism, 7 were unaware of their metabolic abnormality. Among 40 hospitalized patients 50% had abnormal glucose metabolism meanwhile 23.3% of 60 outpatients had this abnormality (p<0.01). No association was seen between BMI, obesity, gender, location and number of SKIN tags with abnormal metabolism of glucose.Conclusion: It is recommended to consider SKIN tags as a cetaceous marker for abnormality of glucose metabolism.

Background and aim: Non-melanoma SKIN cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the SKIN type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these cancers. The objective of this study was to determine NMSC in Isfahan.Materials and Methods: We used data of the cancer resistery center for performing this study and the incidence of NMSC per 100,000 populations was determined. Results: Overall 1681 cases were registered. The incidence of NMSC was calculated to be 10.67/100,000population. The most common site for BCC and SCC was middle face. Conclusion: NMSC incidence in Isfahan is lower than west countries although this incidence is 10.67/100,000in a year. It means that 5-6 thousand cases of NMSC occur in Iran each year. We can prevent its morbidity and mortality by early correct diagnosis.

Introduction & Objective: Median nerve entrapment in the wrist is the most common entrapment neuropathy and is called carpal tunnel SYNDROME (CTS). Conventional electrophysiologic studies evaluate only the myelinated fibers. Sympathetic SKIN response (SSR) is a well- established test for evaluation of the unmyelinated sympathetic fibers. This study was designed to evaluate the sympathetic fibers in CTS. Materials & Methods: Fifty four patients with carpal tunnel SYNDROME and 78 healthy subjects were enrolled in this study. Conventional electrodiangostic studies and SSR were performed in all the subjects with standard method. Results: Latency of the SSR in healthy subjects was 1520.21±87.25 ms and 1637.11 ± 281.13 ms in patients. Conclusion: Unmyelinated sympathetic fibers are involved in CTS and SSR which may, along with other conventional electrophysiologic tests, help in diagnosis of CTS.    

Introduction: Carpal tunnel SYNDROME (CTS) is common disease in the general population and is a complication of several systemic and metabolic diseases. Early diagnosis and treatment of this SYNDROME can prevent its complications such as pain, paresthesia and inability to perform routine works. Sympathetic SKIN Response (SSR) is a simple test for diagnosis of CTS.Methods: This is a descriptive-analytical (case-control) study of 30 patients with unilateral CTS referred to Alzahra Electro-diagnosis Center between May 2002 and September 2003. Unilateral CTS was confirmed with patient history, physical examination and routine DML and DSL tests on median nerves. Then SSR test was performed on both hands and the results were analyzed.Results: The average latency of SSR wave was 1594.7 msec in the affected hands (cases) (SD: ±173.8) and 1585.3 msec in normal hands (SD: ±168.4) (control) (P=0.814). Sensitivity and specificity of SSR amplitude (ASSR) were 13% and 23%, and of latency (LSSR) were 16%and 26% respectively. Discussion: Comparison of SSR test results between normal hands and those with CTS shows that this test has low sensitivity and specificity; hence it cannot be used in diagnosis of CTS. These results correlate with previous studies.

There are no reports of association of specific cutaneous conditions in patients with local recurrent palmar PEELING. Herein, we report a case with characteristic clinical presentation of local recurrent palmar PEELING associated with a port-wine stain lesion. To the best of our knowledge, that association has not been reported before. Interesting points in the presented case are unilateral occurrence of the PEELING disorder and its limitation to the region of port-wine stain.